US-Australia scientists successfully converted cooked eggs back to raw eggs

According to reports from the National Broadcasting Corporation’s Financial Channel, recently researchers from the University of California, Irvine and Flinders University in Australia successfully converted cooked eggs back to raw eggs.

This innovation will greatly reduce the cost of cancer treatment, food production and other parts of the global biotechnology industry, totaling about $160 billion. This study was published in the journal "ChemBioChem".

Restore as long as a few minutes

It is reported that the research team used a variety of different protein materials to try to convert them into usable proteins such as lysozyme. It is well-known that the egg whites of egg become white when cooked, and it is rich in protein. After heating, the long chain of protein unfolds, loses its activity, and then recombines into a tighter and more complex structure. Therefore, the egg white changed from a clear viscous liquid to a white elastic solid.

The researchers at the project discovered a way to disassemble complex protein chains to restore them to their original structure: First, they used a chemical to liquefy the protein of the cooked egg, and then cut tightly-entangled proteins with a vortex jet device. The molecular chains are such that they are normally reconstituted.

"Yes, we invented a method of not cooking eggs," said Grigo Weiss, a professor of chemical molecular biology and biochemistry at the University of California, Irvine, "In the article we describe a way to separate Entangled proteins make them foldable again. We cook egg proteins for 20 minutes at 90 degrees Celsius and restore a key protein in the egg to normal operating conditions."

Like other researchers, Weiss has been working on the efficient production and recovery of valuable molecular proteins. These proteins have a wide range of applications, but they are often formed without correct folding, resulting in the formation of structurally incorrect shapes. Causes them to become almost waste.

"What we are interested in is not the process of handling eggs, but the demonstration of how powerful the process is." Weiss said, "The real problem is that you spend too much time scraping the gel protein from the test tube and you need some This method of recycling this material.” But the common method is very expensive and time-consuming: the molecular level of dialysis takes about 4 days, “and the new process takes only a few minutes, it has accelerated thousands of times.”

Will soon be put on the market

Weiss said: "Our research will not only save a lot of money, but more importantly it will save a lot of time, because time is money." For the application of this technology in cancer treatment, he is particularly optimistic.

One of the cancer treatment technologies is to use lab-made antibodies to attach to cancer cells' proteins so that the immune system can destroy them. Making antibody proteins in the lab is time consuming and expensive. Weiss said that this technology can greatly reduce the time and cost of producing antibody proteins.

For example, pharmaceutical companies are currently creating cancer antibodies on expensive hamster ovary cells. Proteins in these cells generally do not misfold. Rapid and inexpensive promotion of protein processing in the pipeline makes cancer treatment more affordable.

Industrial cheese makers, farmers and other people who use recombinant proteins can also get higher profits.

Currently, the University of California, Irvine, has applied for a patent for this technology and will soon be on the market.

Heated protein lysozyme

Can kill Norovirus

A team of researchers from Tokyo's Ocean University announced recently that heat treatment of egg protein contained lysozyme, which inactivates Norovirus. This is due to the fact that lysozyme can disrupt the coat of Norovirus genes.

Norovirus causes acute gastroenteritis and food poisoning. This virus has a strong infectious power. As long as 10 to 100 virus bodies enter the human body, it will lead to infection. At present, there is no effective antiviral agent.

The team conducted experiments using Norovirus as a substitute for the human Norovirus. They used the lysozyme contained in the protein and heated it at 100 degrees Celsius for 40 minutes to denature it. Next, a solution containing 1% heat-treated lysozyme was mixed with the experimental rat Norovirus, and the change after 1 minute was observed. Lysozyme is an alkaline enzyme that contains a mucopolysaccharide that can hydrolyze pathogenic bacteria.

The researchers found that the norovirus gene amount was reduced so much that it could not be detected and that the virions had expanded. They think this is due to the destruction of the envelope of the viral gene.

The researchers pointed out that the experimental mouse Norovirus and the human Norovirus are very similar genetically, so the heat-denatured protein lysozyme should also have an effect on human Norovirus. They hope to make it into a disinfectant spray, which will be practical in the next year. According to China News Agency, Science and Technology Daily

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Egg white keeps the brain clear

If you are sleepy at the desk in the afternoon, don't eat dessert, and order some eggs. Scientists have discovered that proteins in eggs, especially egg whites, can help keep the brain awake.

Researchers at the University of Cambridge in the United Kingdom have found that eggs can activate these cells by affecting the nutrients in brain cells, allowing them to stay awake and burn calories. Compared to the effects of carbohydrates in chocolate, biscuits, and candy, which increase body energy, proteins in eggs have an advantage.

Therefore, at lunch time, it is best to choose egg white protein-rich foods to provide enough energy for your afternoon work.

Egg protein contains about 12% of protein. Nearly 40 different proteins have been isolated from proteins, of which 24 are low in content.

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